Seminar of Physics of the Living State

(The Applied Physics Scientific Section)


2011 Academic Year

Wednesday, 11 May 2011

Time: 15.30

Oppenheimer Meeting Room, Second Floor, Leonardo Building



Advanced X-ray Micro-tomography Techniques in  Medical Research (*)

Christian Dullin
University Medical Center Göttingen Department of Diagnostic Radiology Göttingen, Germany


(*) Summary. In preclinical research animal models are of great importance to study diseases and develop or test novel treatments. Given the fact that the most part of these models are mouse models, imaging is very challenging due to their littleness. Representing an interdisciplinary group for small animal imaging a variety of applications for CT imaging in mouse models such as tumor therapy models, osteoporosis research and lung imaging will be presented. The applied imaging techniques range from in-vivo flat panel detector based CT's, classical micro CT's to synchrotron radiation as well as image fusion between in-vivo CT and optical imaging. Beside utilizing novel CT techniques, algorithms need to be invented, or adapted to fulfill the needs of small animal imaging. Thus, approaches for semi-automated phenotyping, image fusion, analysis of bone morphology will be presented as well. 

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(**) Biodata: Mr. Christian Dullin is at the University Medical Center Göttingen in the Department of Diagnostic Radiology. He was trained in Technical Physics at Friedrich-Schiller-University in Jena, Germany obtaining his Physics diploma with the reserch topic concerning a 3D skull surface reconstruction out of MRI data sets in a university collaboration with the  German company that is developing individually designed hard tissue implants (3di GmbH).
    He was research assistant at the Diagnostic Radiology, University Medical Center Göttingen. His duty included to be in charge of experimental small animal imaging (CT and optical techniques), including software development and data analysis in various applications. He is a member of the German Network for Molecular Imaging. Mr. Dullin has presented his own work in different scientific international meetings.